| 摘要 |
THE PRESENT INVENTION RELATES TO THE USE OF A SUBSTITUTED QUINOLINE DERIVATIVE FOR THE PREPARATION OF A MEDICAMENT FOR THE TREATMENT OF AN INFECTION WITH A DRUG RESISTANT MYCOBACTERIUM STRAIN WHEREIN THE SUBSTITUTED QUINOLINE DERIVATIVE IS A COMPOUND ACCORDING TO FORMULA (IA) OR FORMULA (IB) THE PHANNACEUTICALLY ACCEPTABLE ACID OR BASE ADDITION SALTS THEREOF, THE STEREO CHEMICALLY ISOMERIC FOMLS THEREOF, THE TAUTOMERIC FOMLS THEREOF AND THE N-OXIDE FOMLS THEREOF. ALSO CLAIMED IS A COMPOSITION COMPRISING A PHANNACEUTICALLY ACCEPTABLE CARRIER AND, AS ACTIVE INGREDIENT, A THERAPEUTICALLY EFFECTIVE AMOUNT OF THE ABOVE COMPOUNDS AND ONE OR MORE OTHER ANTIMYCOBACTERIAL AGENTS. |
