A POWDERY COMPOSITION AND A METHOD FOR PRODUCING THEREOF, A PHARMACEUTICAL DRUG AND A METHOD FOR PRODUCING THEREOF, USE OF AMORPHOUS SILICA

摘要

A powdery composition is proposed comprising a steroidal molecule and a pharmaceutically acceptable carrier having a specific surface area of at least 200 m/g; wherein the steroidal molecule is dispersed in a solvent adsorbed on the surface of the pharmaceutically acceptable carrier and wherein the steroidal molecule is present in the solvent in a supersaturated concentration. A method for producing said composition and a pharmaceutical drug in the form of granules, a tablet, a capsule or a pill comprising the composition, and also a method for producing the tablet are proposed. In addition, use of amorphous silica with a specific surface area greater than 250 m/g for inhibiting re-crystallisation of a steroidal molecule that is present in a solvent in a supersaturated concentration is proposed.