发明名称 THERAPEUTIC AGENT FOR INTESTINAL TRACT INJURY ACCOMPANYING ADMINISTRATION OF A NON-STEROID ANTI-INFLAMMATORY AGENT
摘要 <p>Disclosed is a pharmaceutical composition for treating intestinal tract injury accompanying administration of a non-steroid anti-inflammatory agent. Disclosed is a pharmaceutical composition for treating intestinal tract injury accompanying administration of a non-steroid anti-inflammatory agent, which contains as an active ingredient a heterocyclic derivative represented by general formula (1) or a pharmaceutically acceptable salt thereof. [EQUATION 1] In formula (1), R1 and R2, which can be the same or different, represent an optionally substituted aryl, R3 and R4, which can be the same or different, represent a hydrogen atom or alkyl, R5 represents a hydrogen atom, alkyl or a halogen atom, Y represents N or N?O, A represents NR6, R6 represents a hydrogen atom, alkyl or the like, D represents an optionally hydroxy substituted alkylene or alkenylene, E represents phenylene or a single bond, G represents O, S, or the like, and Q represents carboxy, alkoxycarbonyl, or the like.</p>
申请公布号 WO2009157397(A1) 申请公布日期 2009.12.30
申请号 WO2009JP61286 申请日期 2009.06.22
申请人 NIPPON SHINYAKU CO., LTD.;KYOI, TAKASHI 发明人 KYOI, TAKASHI
分类号 A61K31/4965;A61P1/04;C07D241/20 主分类号 A61K31/4965
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