发明名称 (Indol-3-yl)-heterocycle derivatives as agonists of the cannabinoid cb1 receptor
摘要 Disclosed is an indole derivative of formula I, or a pharmaceutically acceptable salt thereof, wherein A is a 5-membered aromatic heterocyclic ring, with X1, X2, and X3 each being N, O, S, or CR, Y is CH2, O, S, or SO2, R1 is C1-4alkyl, C1-4alkyloxy, CN, or halogen, R2 and R3 may together form a 4-7 membered ring, R3 and R4 may together form a 4-8 membered ring, and wherein the other substituents are as described in the specification. Also described is the use of the compound for treating pain.
申请公布号 NZ566007(A) 申请公布日期 2009.12.24
申请号 NZ20060566007 申请日期 2006.08.21
申请人 N.V. ORGANON 发明人 RATCLIFFE, PAUL DAVID;ADAM-WORRALL, JULIA;MORRISON, ANGUS JOHN;FRANCIS, STUART JOHN;KIYOI, TAKAO
分类号 A61K31/4245;A61K31/433;A61P29/00;C07D413/14;C07D417/14 主分类号 A61K31/4245
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