| 发明名称 |
HUMANIZED ANTIBODY TO INTERFERON ALPHA RECEPTOR (IFNAR-1) |
| 摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide a medical agent and the like effective for inhibiting a type I IFN activity. <P>SOLUTION: A humanized monoclonal antibody which binds to IFNAR-1, and a related antibody-based composition and a molecule are provided. Also provide are a pharmaceutical composition comprising the humanized antibody, and a therapeutic diagnostic method for using the humanized antibody. <P>COPYRIGHT: (C)2010,JPO&INPIT</p> |
| 申请公布号 |
JP2009298818(A) |
申请公布日期 |
2009.12.24 |
| 申请号 |
JP20090223533 |
申请日期 |
2009.09.28 |
| 申请人 |
MEDAREX INC |
发明人 |
CARDARELLI JOSEPHINE M;CHEN TSENG-HUI TIMOTHY;KING DAVID;BEBBINGTON CHRISTOPHER R;POGUE SARAH LEE;CARR FRANCIS J;WILLIAMS STEPHEN |
| 分类号 |
C07K16/46;A61K39/00;A61K39/395;A61P3/10;A61P13/12;A61P17/06;A61P25/00;A61P29/00;A61P37/04;C07K16/28;C07K16/44;C12N15/09;C12P21/08 |
主分类号 |
C07K16/46 |
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