发明名称 QUINAZOLINE ANALOGS AS RECEPTOR TYROSINE KINASE INHIBITORS
摘要 This invention provides quinazoline analogs of Formula (I): where A is bonded to at least one of the carbons at the 5, 6, 7 or 8 position of the bicyclic ring, and the ring is substituted by up to two independent R3 groups. The invention also includes methods of using compounds of Formula (I) as type I receptor tyrosine kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.
申请公布号 CA2535614(C) 申请公布日期 2009.12.22
申请号 CA20042535614 申请日期 2004.08.10
申请人 ARRAY BIOPHARMA INC. 发明人 BUCKMELTER, ALEXANDRE;ZHAO, QIAN;TOPALOV, GEORGE;WALLACE, ELI;LYSSIKATOS, JOSEPH
分类号 C07D413/14;A61K31/517;A61P35/00;C07D239/94;C07D401/12;C07D413/12;C07D417/14;C07D498/02;C07D498/04;C07D498/08 主分类号 C07D413/14
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