发明名称 Peptides having ligand activities on APJ that is an orphan G protein-coupled receptor, and use thereof
摘要 The present invention relates to novel peptide derivatives, which are recognized as ligands to G-coupled protein receptor proteins. The peptide of the present invention can be used in (1) development of a receptor binding assay system using the expression system of the recombinant receptor protein and screening of candidates for pharmaceutical compounds, and (2) development of pharmaceutical preparations such as a neutral nerve function regulator, a circulatory function regulator, a cardiac function regulator, an immune function regulator, a digestive organ function regulator, a metabolic function regulator, a generative organ regulator or the like.
申请公布号 US7635751(B2) 申请公布日期 2009.12.22
申请号 US20020239321 申请日期 2002.09.19
申请人 TAKADA PHARMACEUTICAL COMPANY LIMITED 发明人 KITADA CHIEKO;NISHIZAWA NAOKI;HINUMA SHUJI;HOSOYA MASAKI
分类号 A61K38/00;C07K7/06;A61K38/08;A61K38/10;A61P1/00;A61P1/18;A61P3/00;A61P3/10;A61P9/00;A61P9/14;A61P15/00;A61P25/00;A61P25/28;A61P31/18;A61P37/02;C07K7/08;C07K14/47 主分类号 A61K38/00
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