发明名称 PROMPT NUCLEIC ACID DELIVERY CARRIER COMPOSITION
摘要 <p>Disclosed is a nucleic acid delivery carrier which can deliver a nucleic acid (e.g., siRNA) into a cell with high efficiency when the nucleic acid is administered to an animal-derived cell or an animal body, and which is less toxic and highly safe. Also disclosed is a nucleic acid delivery composition comprising the carrier and a nucleic acid. The nucleic acid delivery carrier comprises a combination of (A) diacylphosphatidyl choline, (B) at least one member selected from the group consisting of cholesterol and a derivative thereof, and (C) an aliphatic primary amine. A nucleic acid delivery composition can be prepared by mixing the nucleic acid delivery carrier with a nucleic acid.</p>
申请公布号 KR20090130056(A) 申请公布日期 2009.12.17
申请号 KR20097021571 申请日期 2008.03.26
申请人 TAKEUCHI HIROFUMI;OTSUKA PHARMACEUTICAL CO., LTD. 发明人 TAKEUCHI HIROFUMI;HIRA YASUYUKI;NAKANO KOJI;TOYOBUKU HIDEKAZU
分类号 A61K47/24;A61K31/7105;A61K47/18;A61K48/00 主分类号 A61K47/24
代理机构 代理人
主权项
地址