发明名称 OXAZOLIDINONE ANTIBIOTIC DERIVATIVES
摘要 The invention relates to antibacterial compounds of formula (I) wherein Ris hydrogen, halogen, hydroxy, alkoxy or cyano; Yand Yeach represent CH, one or two of U, V, W and X represent(s) N and the remaining each represent CH or, in the case of X, may also represent CR, Rbeing halogen, and, in the case of W, may also represent CR, or each of U, V, W, X, Yand Yrepresents CH, or each of U, V, W, X and Yrepresents CH and Yrepresents N, or also one or, provided Ris hydrogen, two of U, V, W, X, Yand Yrepresent(s) CRC and the remaining each represent CH, Rbeing alkoxy, alkoxycarbonyl or alkoxyalkoxy and Rbeing, each time it occurs, independently represents hydroxy or alkoxy; A-B-D represents a chain of 4 to 6 atoms, which 4 to 6 atoms are seleted from carbon, oxygen and nitrogen and may be substituted; E is one of the following groups: in which Z is CH or N and Q is O or S, or E is a phenyl group which is substituted once or twice in the meta and/or para position(s); and to salts of such compounds.
申请公布号 KR20090130112(A) 申请公布日期 2009.12.17
申请号 KR20097023303 申请日期 2008.04.10
申请人 ACTELION PHARMACEUTICALS LTD. 发明人 GUDE MARKUS;HUBSCHWERLEN CHRISTIAN;RUEEDI GEORG;SURIVET JEAN PHILIPPE;ZUMBRUNN ACKLIN CORNELIA
分类号 C07D471/04;A61K31/4375;A61P31/04;C07D417/14 主分类号 C07D471/04
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