发明名称 CANCER THERAPY USING BCL-XL-SPECIFIC SINA
摘要 The invention relates to a double-stranded short interfering nucleic acid (siNA) molecule specific to the Bcl-XL transcript, comprising a sense and an antisense region, wherein the sense region comprises the nucleotide sequence SEQ ID NO: 1 or a sequence having at least 70% identity, preferably at least 80% identity, more preferably at least 90% identity with said sequence, and the antisense region comprises a nucleotide sequence that is complementary to the sense region, and its use for treating cancer.
申请公布号 US2009312393(A1) 申请公布日期 2009.12.17
申请号 US20070306093 申请日期 2007.06.22
申请人 CENTRE REGIONAL DE LUTTE CONTRE LE CANCER - CENTRE FRANCOIS BACLESSE 发明人 POULAIN LAURENT;GAUDUCHON PASCAL;BROTIN EMILIE;SAISON-BEHMOARAS ESTER
分类号 A61K31/713;A61P35/00;C07H21/02;C12N5/10;C12N15/11;C12N15/113;C12N15/85 主分类号 A61K31/713
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