摘要 |
<P>PROBLEM TO BE SOLVED: To provide a multi-well filter with reduced capillary holdup. Ž<P>SOLUTION: The multi-well filtering device comprises a filter plate having a plurality of wells, each including a support. Each well has a corresponding adjacent access port providing access means to the bottom of the corresponding feeding/receiver plate well, (e.g. via a pipette chip). When the filter plate is positioned over a feeding/receiver well plate having a plurality of wells, the plurality of wells align with and communicates with a corresponding well of the corresponding filter plate. Each access port provides access means to a respective well in the feeding/receiver plate well, and when the filter plate is positioned over feeding/receiver well plate, the relative position of the filter plate well are not centrally located with respect to the feeding/receiver plate wells, but are shifted in the x and y directions relative to the receiver wells in an amount effective for reducing or eliminating capillary holdup in the gap between the filter wells and the feeding/receiver wells. The wells in the feeding/receiver plate well preferably are formed in a U-shaped bottom below each access port. Ž<P>COPYRIGHT: (C)2010,JPO&INPIT Ž
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