METHOD OF PREPARING AN IMMUNOLOGICALLY-ACTIVE ADJUVANT-BOUND DRIED VACCINE COMPOSITION
摘要
<p>The disclosure provides a method of preparing an immunologically-active adjuvant-bound freeze dried vaccine composition. A specific embodiment provides a stable vaccine composition comprising an aluminum-salt adjuvant, a recombinant Clostridium botulinum neurotoxin protein and a glass-forming agent. These vaccine compositions are useful in the treatment of humans and other animals at risk of infection from Clostridium botulinum neurotoxin.</p>
申请公布号
EP2131857(A2)
申请公布日期
2009.12.16
申请号
EP20080732401
申请日期
2008.03.18
申请人
THE REGENTS OF THE UNIVERSITY OF COLORADO
发明人
RANDOLPH, THEODORE, W.;CLAUSI, AMBER;CARPENTER, JOHN, F.;SCHWARTZ, DANIEL, K.