摘要 |
The present invention relates to novel pyrazole and benzoxazole-substituted pyridine derivatives or pharmaceutically acceptable salts thereof, a preparation process for same, and a pharmaceutical composition for preventing and treating disorders involving aberrant cell proliferation containing the same as active ingredients. The present invention exhibits superior effects of inhibiting a wide variety of protein kinases, for example, c-Met, Ron, KDR, Lck, Flt1, Flt3, Tie2, TrkA, TrkB, b-Raf, Aurora-A and the like which are useful for treatment of disorders involving aberrant cell proliferation, and therefore can be valuably used for the prevention and treatment of disorders involving aberrant cell proliferation.
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申请人 |
KOREA RESERACH INSTITUTE OF CHEMICAL TECHNOLOGY;KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY;KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY;KOH, JONG SUNG;LEE, JONG KOOK;CHO, SUNG YUN;HAN, SUN-YOUNG;LEE, CHONG OCK;RYU, JAE WOOK;PARK, KYUNG CHAN;HAN, DONG CHO;HA, JAE DU;PARK, SONG-KYU;JUNG, HEE JUNG;KWON, BYOUNG-MOG;YOO, KYUNG HO;SIM, TAEBO |
发明人 |
KOH, JONG SUNG;LEE, JONG KOOK;CHO, SUNG YUN;HAN, SUN-YOUNG;LEE, CHONG OCK;RYU, JAE WOOK;PARK, KYUNG CHAN;HAN, DONG CHO;HA, JAE DU;PARK, SONG-KYU;JUNG, HEE JUNG;KWON, BYOUNG-MOG;YOO, KYUNG HO;SIM, TAEBO |