发明名称 INDOLE COMPOUNDS HAVING C4-AMIDE SUBSTITUENTS AND USE THEREOF AS PHOSPHOLIPASE-A2 INHIBITORS
摘要 Indole and indole-related compounds according to the formula (I) or (II) optionally having additional heteroatoms, compositions and methods are disclosed. The compounds of the invention are useful as phospholipase inhibitors. The compounds and compositions of the invention are useful for treatment of phospholipase-related conditions, such as insulin-related, weight-related and/or cholesterol-related conditions in an animal subject. Formula (I), formula (II). R4 being a moiety represented by formula (C4-II-C), R3 being a moiety represented by formula (C3-I or C3-II).
申请公布号 US2009306171(A1) 申请公布日期 2009.12.10
申请号 US20060092388 申请日期 2006.11.03
申请人 CHANG HAN-TING;CHARMOT DOMINIQUE;GLINKA TOMASZ;COPE MICHAEL JAMES;GOKA ELIZABETH;SHAO JUN;CHEN SHIAH-YUN;BUYSSE JERRY M 发明人 CHANG HAN-TING;CHARMOT DOMINIQUE;GLINKA TOMASZ;COPE MICHAEL JAMES;GOKA ELIZABETH;SHAO JUN;CHEN SHIAH-YUN;BUYSSE JERRY M.
分类号 A61K31/404;C07D209/20 主分类号 A61K31/404
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