发明名称 Nitroxyalkylamide derivatives
摘要 PCT No. PCT/JP92/01419 Sec. 371 Date Jul. 25, 1994 Sec. 102(e) Date Jul. 25, 1994 PCT Filed Nov. 2, 1992 PCT Pub. No. WO93/09085 PCT Pub. Date May 13, 1993Nitroxyalkylamide compounds having the formula: R1-(A)n-CONH-B'-ONO2 wherein R1 is an optionally substituted furyl, furyloxy, thienyl, thienyloxy, isoxazolyl, phenoxy, phenylthio or 1,4-dibenzodioxanyl, A is a C1-C4 alkylene group; B' is a C1-C4 alkylene group; and n is 0 or 1. The compounds of the present invention have a desirable vasodilator action for collateral vessels and an anti-anginal action, and are useful as therapeutic agents for treating angina pectoris.
申请公布号 US5580893(A) 申请公布日期 1996.12.03
申请号 US19940211904 申请日期 1994.07.25
申请人 SANKYO COMPANY, LIMITED 发明人 ISHIHARA, SADAO;SAITO, FUJIO;KATAOKA, MITSURU;KOIKE, HIROYUKI;MIYAKE, SHIGEKI;MIZUNO, HIROSHI
分类号 A61K31/16;A61K31/27;A61K31/34;A61K31/341;A61K31/38;A61K31/381;A61K31/41;A61P9/08;A61P9/10;C07C233/08;C07C233/13;C07C235/20;C07C235/22;C07C271/48;C07C323/60;C07C323/62;C07C333/04;C07D261/08;C07D261/10;C07D261/12;C07D307/54;C07D307/68;C07D307/71;C07D319/20;C07D333/38;(IPC1-7):A61K31/41;C07D261/06 主分类号 A61K31/16
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