发明名称 Substituted monocyclic CGRP receptor antagonists
摘要 Compounds of formula I: (wherein variables A1, A2, A3, A4, m, n, J, Q, R4, Ea, Eb, Ec, R6, R7, Re, Rf, RPG and Y are as described herein) which are antagonists of CGRP receptors and which are useful in the treatment or prevention of diseases in which the CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
申请公布号 US7625901(B2) 申请公布日期 2009.12.01
申请号 US20080214460 申请日期 2008.06.19
申请人 MERCK & CO., INC. 发明人 WOOD MICHAEL R.;GALLICCHIO STEVEN N.;SELNICK HAROLD G.;ZARTMAN C. BLAIR;BELL IAN M.;STUMP CRAIG A.
分类号 C07D401/12;A61K31/4188;A61K31/438;A61K31/4439;A61K31/4965;A61K31/499;A61P25/06;C07D409/14;C07D413/12;C07D471/04;C07D471/20;C07D519/00 主分类号 C07D401/12
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