发明名称 (1Z,3Z)-4-ARYL-4-HYDROXY-1-(3,3-DIALKYL-3,4-DIHYDROISOQUINOLIN-1(2N)-YLIDENE)-BUT-3-EN-4-ONES AND METHOD OF PRODUCING SAID COMPOUNDS
摘要 FIELD: chemistry. ^ SUBSTANCE: invention relates to organic chemistry, specifically to new compounds (1Z,3Z)-4-aryl-4-hydroxy-1-(3,3-dialkyl-3,4-dihydroisoquinolin-1(2N)-ylidene)-but-3-en-4-ones with general formula: ^ ^ III: R=H, Alk1=Alk2=Me, Ar=Ph (a), Ar=C6H4Me-p (b), Alk1=Me, Alk2=Bu, Ar=Ph (c), Ar=C6H4Me-p (d), R=OMe, Alk1=Alk2=Me, Ar=Ph (e), Ar=C6H4Me-p (f), R=OEt, Alk1=Alk2=Me, Ar=Ph (g). The invention also relates to a method of producing said compounds. ^ EFFECT: obtaining new compounds with analgetic activity and which can be used as primary products in synthesis of new heterocyclic systems. ^ 4 cl, 1 tbl, 8 ex
申请公布号 RU2374231(C1) 申请公布日期 2009.11.27
申请号 RU20080145610 申请日期 2008.11.19
申请人 GOSUDARSTVENNOE OBRAZOVATEL'NOE UCHREZHDENIE VYSSHEGO PROFESSIONAL'NOGO OBRAZOVANIJA "PERMSKIJ GOSUDARSTVENNYJ UNIVERSITET" 发明人 KHALTURINA VALERIJA VLADISLAVOVNA;SHKLJAEV JURIJ VLADIMIROVICH;MASLIVETS ANDREJ NIKOLAEVICH;MAKHMUDOV RAMIZ RAGIPOVICH
分类号 A61K31/472;A61P29/00;C07D217/12;C07D217/24 主分类号 A61K31/472
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