发明名称 |
PROCESS FOR THE PREPARATION OF A BETA-LACTAM ANTIBIOTIC WITH MUTATED PENICILLIN ACYLASE. |
摘要 |
<p>The invention relates to mutated penicillin acylases having a high synthesis/hydrolysis ratio in comparison with wild-type penicillin acylases and at least 1% of the activity. The invention also relates to a process for the enzymatic preparation of a ß-lactam antibiotic from a ß-lactam nucleus and an activated side chain with the aid of mutated penicillin acylases.</p> |
申请公布号 |
MXPA04006304(A) |
申请公布日期 |
2004.10.04 |
申请号 |
MX2004PA06304 |
申请日期 |
2002.12.18 |
申请人 |
DSM IP ASSETS B.V. |
发明人 |
THEODORUS JOHANNES GODFRIED MARIA DOOREN VAN |
分类号 |
C12N1/21;C12N9/84;C12N15/55;(IPC1-7):C12N9/84 |
主分类号 |
C12N1/21 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|