PREDICTORS OF PATIENT RESPONSE TO TREATMENT WITH EGF RECEPTOR INHIBITORS
摘要
The present invention provides methods and compositions to facilitate determining whether an EGFR-expressing cancer in an individual is an EGFR inhibitor-responsive cancer, as well as methods for determining the likelihood that a patient having an EGFR-expressing cancer will exhibit a beneficial response to an EGFR inhibitor therapy. The methods generally involve determining a normalized expression level of a gene product that correlates with EGFR inhibitor responsiveness.
申请公布号
CA2723984(A1)
申请公布日期
2009.11.19
申请号
CA20092723984
申请日期
2009.05.13
申请人
GENOMIC HEALTH INC.;BRISTOL-MYERS SQUIBB COMPANY
发明人
BAKER, JOFFRE B.;WATSON, DREW;MADDALA, TARA;SHAK, STEVEN;MAURO, DAVID J.;FORD, SHIRIN K.