| 发明名称 |
PROCESS FOR THE PREPARTION OF TENOFOVIR |
| 摘要 |
The present invention relates to novel Tenofovir disoproxil hemifumarate salt, which is prepared by dealkylation of Phosphonate esters by using mineral acids followed by esterification and crystallization to give crystalline Tenofovir disoproxil. The Tenofovir disoproxil is further converted to fumarate salts with improved yield.
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| 申请公布号 |
US2009286981(A1) |
申请公布日期 |
2009.11.19 |
| 申请号 |
US20090352182 |
申请日期 |
2009.01.12 |
| 申请人 |
VASIREDDY UMA MAHESWER RAO;VELLANKI SIVA RAMA PRASAD;BALUSU RAJA BABU;BANDI NAGA DURGA RAO;JUJJAVARAPU PAVAN KUMAR;GINJUPALLI SAMBASIVA RAO;PILLI RAMA KRISHNA |
发明人 |
VASIREDDY UMA MAHESWER RAO;VELLANKI SIVA RAMA PRASAD;BALUSU RAJA BABU;BANDI NAGA DURGA RAO;JUJJAVARAPU PAVAN KUMAR;GINJUPALLI SAMBASIVA RAO;PILLI RAMA KRISHNA |
| 分类号 |
C07F9/6561 |
主分类号 |
C07F9/6561 |
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