| 发明名称 |
Modulation of HIF-1 beta expression |
| 摘要 |
Compounds, compositions and methods are provided for modulating the expression of HIF1-beta. The compositions comprise oligonucleotides, targeted to nucleic acid encoding HIF1-beta. Methods of using these compounds for modulation of HIF1-beta expression and for diagnosis and treatment of diseases and conditions associated with expression of HIF1-beta are provided.
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| 申请公布号 |
US7618947(B2) |
申请公布日期 |
2009.11.17 |
| 申请号 |
US20050213593 |
申请日期 |
2005.08.25 |
| 申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
MARCUSSON ERIC G.;HENRY SCOTT W.;KIM YOUNGSOO;DOBIE KENNETH W. |
| 分类号 |
A61K31/70;C07H21/02;C07H21/04;C12Q1/68 |
主分类号 |
A61K31/70 |
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