发明名称 |
TRISUBSTITUTED PYRAZOLES AS ACETYLCHOLINE RECEPTOR MODULATORS |
摘要 |
<p>The present invention relates to 1-alkyl-3-aniline-5-aryl-pyrazole derivatives and pharmaceutically acceptable salts thereof, processes for preparing them, pharmaceutical compositions containing them and their use in therapy, according to Formula (I). The invention particularly relates to positive allosteric modulators of nicotinic acetylcholine receptors, such positive allosteric modulator having the capability to increase the efficacy of nicotinic receptor agonists.</p> |
申请公布号 |
WO2009135944(A1) |
申请公布日期 |
2009.11.12 |
申请号 |
WO2009EP55617 |
申请日期 |
2009.05.08 |
申请人 |
JANSSEN PHARMACEUTICA NV;THURING, JOHANNES WILHELMUS JOHN F.;MACDONALD, GREGOR, JAMES;ZHUANG, WEI |
发明人 |
THURING, JOHANNES WILHELMUS JOHN F.;MACDONALD, GREGOR, JAMES;ZHUANG, WEI |
分类号 |
C07D231/38;A61K31/455;A61P25/00;C07D401/04;C07D407/04;C07D407/14 |
主分类号 |
C07D231/38 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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