NOVEL 1-PHENYL-CARBOXYLIC ACID ESTER DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREOF AND MUSCARINIC RECEPTOR ANTAGONIST OR PHARMACEUTICAL COMPOSITION FOR THE PREVENTION AND TREATMENT OF NERVOUS SYSTEM DISEASES BY ORGANOPHOSPHATE INTOXICATION CONTAINING THE SAME AS AN ACTIVE INGREDIENT

摘要

PURPOSE: A pharmaceutical composition for preventing and treating nervous system disease caused by organophosphate compound or mucarine receptor antagonist is provided to prevent and treat nerve system diseases such as convulsion, Parkison's disease, and epilepsy. CONSTITUTION: A novel 1-phenyl-carboxylic acid ester derivative is denoted by the chemical formula 1. In the chemical formula 1, X is hydrogen, halogen, amino, nitro, straight or branched alkyl of C1-C5 or alkoxy of C1-C5. A method for producing 1-phenyl-carboxylic acid ester derivative comprises: a step of reacting thionyl chloride with carboxylic acid of the chemical formula 2 to obtain a compound of the chemical formula 3; and a step of performing esterification of a compound of the chemical formula 3 and a compound of the chemical formula 4 to obtain a derivative of the chemical formula 1.