Method and device for controlling fluid flow through a sample processing device

摘要

A method and device for controlling fluid flow through a sample processing device, comprising:
providing a sample processing device comprising a substrate (180) that comprises first and second major sides and a first cover (184) attached to the first major side of the substrate, the sample processing device further comprising a process array formed therein, the process array comprising a first chamber (150a) defining a first chamber volume, a second chamber, a channel (160b) extending between the first chamber and the second chamber, and a valve tip (172a) protruding into the first chamber volume of the first chamber, wherein the valve lip separates the first chamber from the channel, wherein the valve lip is located between a portion of the first chamber volume and the first cover, and wherein the portion of the first chamber volume is located between the valve hp and the second major side of the substrate;
forming an opening in the valve tip, wherein the first chamber is in fluid communication with the channel after forming the opening; and
rotating the sample processing device about an axis of rotation after forming the opening to move sample material from the first chamber into the channel through the opening.