发明名称 |
IN VIVO IMAGING AGENTS FOR MET RECEPTOR TYROSINE KINASE |
摘要 |
Provided are in vivo imaging agents comprising muteins of hTLc having detectable binding affinity for c-Met or a domain thereof, coupled to a signal generator, and the mutein coupled to a signal generator is disposed in a pharmaceutically acceptable carrier. Also provided are diagnostic methods using in vivo imaging agents comprising muteins of hTLc having detectable binding affinity for c-Met or a domain thereof.
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申请公布号 |
US2009274623(A1) |
申请公布日期 |
2009.11.05 |
申请号 |
US20080022526 |
申请日期 |
2008.01.30 |
申请人 |
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发明人 |
SMITH CLIFFORD L.;SYUD FAISAL AHMED;LEE BRIAN DUH-LAN;MORRISON MATTHEW SAM;MARINO MICHAEL ERNEST;CASTLE JASON WILLIAM;SCHAFFER PAUL;MATSCHINER GABRIELE;HOHLBAUM ANDREAS;HUELSMEYER MARTIN;TRENTMANN STEFAN |
分类号 |
A61K51/08;A61K49/00;A61K49/14 |
主分类号 |
A61K51/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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