USE OF SFRP-3 IN THE ASSESSMENT OF HEART FAILURE

摘要

The invention relates to a method for assessing heart failure in vitro comprising the steps of measuring in a sample the concentration of the marker SFRP-3, of optionally measuring in the sample the concentration of one or more other marker (s) of heart failure, and of assessing heart failure by comparing the concentration determined in for SFRP-3 and the concentration (s) determined for the optionally one or more other marker to the concentration of this marker or these markers as established in a reference population. Also disclosed are the use of SFRP-3 as a marker protein in the assessment of heart failure, a marker combination comprising SFRP-3 and a kit for measuring SFRP-3. The other optimal markers are selected from: natriuretic peptide marker, a cardiac troponin marker, a marker of inflammation, NT-proBNP, and troponin T.