发明名称 |
HEPARIN-CONJUGATED FIBRIN GEL AND METHOD AND KIT FOR PREPARING THE SAME |
摘要 |
A method of preparing a heparin-conjugated fibrin gel is provided, which includes activating heparin, conjugating the activated heparin with fibrinogen to prepare heparin-conjugated fibrinogen, mixing free fibrinogen with the heparin-conjugated fibrinogen to prepare a fibrinogen mixture, and mixing thrombin with the fibrinogen mixture. In addition, a heparin-conjugated fibrin gel prepared by the above method and a kit for preparing the same are provided. According to the method of preparing the heparin-conjugated fibrin gel, the heparin-conjugated fibrin gel having an affinity for drugs such as growth factors may be easily prepared at low costs, and can also be used as a therapeutic drug excellently effective on generation of tissues such as bones, skin, blood vessels, cartilages, etc. by sustainably releasing drugs such as growth factors to a local site for a long period of time through injection into a human body. |
申请公布号 |
WO2009134054(A2) |
申请公布日期 |
2009.11.05 |
申请号 |
WO2009KR02220 |
申请日期 |
2009.04.28 |
申请人 |
INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY;KIM, BYUNG-SOO;JEON, O-JU;YANG, HEE-SEOK |
发明人 |
KIM, BYUNG-SOO;JEON, O-JU;YANG, HEE-SEOK |
分类号 |
A61L27/38;A61F2/02;A61F2/10;A61L27/60 |
主分类号 |
A61L27/38 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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