摘要 |
A method for providing new therapeutic agent(s) that comprises the following steps: a) selecting at least one polypeptide encoded by a natural allelic variant of one preselected gene with therapeutic potential and/or of at least one related gene(s) thereof; b) determining the therapeutic index of the polypeptide(s) selected in step a); and c) retaining as a therapeutic agent(s), the polypeptide(s) selected in step a), whose therapeutic index, as determined in step b), is higher than a therapeutic index of reference. |