METHOD FOR PRODUCING GLYCATED PROTEINACEOUS MOLECULE CONSISTING OF A LEWIS X STRUCTURE, A SIALYL-LEWIS X STRUCTURE AND/OR LACDINAC STRUCTURE

摘要

The present invention relates to a method for producing a glycated proteinaceous molecule consisting of a Lewis x, a sialyl Lewis x and/or a LacdiNAc structure, comprising proteinaceous molecule expression in mammalian cells which comprise a nucleic acid encoding the E1 region, or a part thereof, human adenovirus providing said providing said proteinaceous molecule expression, and purifying said proteinaceous molecule from the mammalian cell culture, wherein said purification comprises a step at which said Lewis x, said sialyl Lewis x and/or said LacdiNAc structure is used.