发明名称 |
QUINAZOLINE ANALOGS AS RECEPTOR TYROSINE KINASE INHIBITORS |
摘要 |
This invention concerns quinazoline analogs of Formula I: where an A group is bonded to at least one of the carbons at the 5, 6, 7 or 8 position of the bicyclic ring, and the ring is substituted by up to three independent R3 groups. The invention also includes methods of using these compounds as type I receptor tyrosine kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.
|
申请公布号 |
US2009270621(A1) |
申请公布日期 |
2009.10.29 |
申请号 |
US20090496973 |
申请日期 |
2009.07.02 |
申请人 |
ARRAY BIOPHARMA, INC. |
发明人 |
WALLACE ELI;TOPALOV GEORGE;LYSSIKATOS JOSEPH;BUCKMELTER ALEXANDRE;ZHAO QIAN |
分类号 |
C07D413/12;C07D239/72;C07D239/94;C07D401/12;C07D403/12;C07D413/14;C07D417/14;C07D498/04;C07D498/08 |
主分类号 |
C07D413/12 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|