Morpholine type cinnamide compound

摘要

Compounds of the formula: (I) [wherein R<1>, R<2>, R<3> and R<4> either identical with or different from each other are a hydrogen atom or a C1-C6 alkyl; X1 is an optionally substituted C1-C6 alkylene; Xa is a methoxy group or fluorine atom; Xb is an oxygen atom or methylene group (provided that when Xa is methoxy, Xb is limited to an oxygen atom); and Ar1 is an aryl, pyridinyl, aryloxy or pyridinyloxy, optionally having a substituent, such as a halogen atom], and pharmacologically acceptable salts thereof, and use thereof as pharmaceuticals.