发明名称 |
Breaking immunological toterance with a genetically encoded unnatural amino acid |
摘要 |
The present invention comprises methods and compositions for producing and/or enhancing an immunological response in a subject against a target moiety such as a disease-related moiety by administration of an antigenic version of the target moiety having one or more unnatural amino acid and/or by administration of an antibody against a version of a target moiety having one or more unnatural amino acid which antibody is cross reactive with the natural target moiety.
|
申请公布号 |
US2009263376(A1) |
申请公布日期 |
2009.10.22 |
申请号 |
US20090322938 |
申请日期 |
2009.02.07 |
申请人 |
THE SCRIPPS RESEARCH INSTITUTE |
发明人 |
GRUNEWALD JAN;TSAO MENG-LIN;PERERA ROSHAN;LERNER RICHARD A.;SMIDER VAUGHN V.;SCHULTZ PETER G. |
分类号 |
A61K39/395;A61K39/00;A61K39/02;A61K39/12;C07K14/00;C12P21/00 |
主分类号 |
A61K39/395 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|