发明名称 |
ANTIBODY TARGETING OSTEOCLAST-ASSOCIATED PROTEIN |
摘要 |
<p>The present invention relates to a method of detecting metabolic bone disorders using a gene expressed at a high level in osteoclasts, a method of screening for a compound effective for treatment and/or prevention of metabolic bone disorders, and a pharmaceutical composition for treatment and/or prevention of metabolic bone disorders. Specifically, the present invention relates to a method of detecting metabolic bone disorders using expression of the human DC-STAMP gene as an indicator, a pharmaceutical composition containing an antibody which is capable of specifically recognizing human DC-STAMP and suppressing formation of osteoclasts, and so forth.</p> |
申请公布号 |
EP1715038(A4) |
申请公布日期 |
2009.10.21 |
申请号 |
EP20050710273 |
申请日期 |
2005.02.09 |
申请人 |
SANKYO COMPANY, LIMITED |
发明人 |
NOMIYAMA, HISAYUKI;KUKITA, TOSHIO;HIRUMA, YOSHIHARU |
分类号 |
C07K16/28;A61K39/395;A61K48/00;A61P19/08;A61P19/10;A61P29/00;A61P35/00;C12N15/09;C12P21/08;C12Q1/68;G01N33/15;G01N33/50;G01N33/53 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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