发明名称 Fatty acid formulations for oral delivery of proteins and peptides, and uses thereof
摘要 Fatty acid compositions for administration of of pharmaceutical agents, such as proteins and peptides, protein and peptide conjugates, and/or cation-polypeptide conjugate complexes. In particular, the invention provides a solid pharmaceutical composition formulated for oral administration by ingestion, having from about 0.1 to about 75% w/w fatty acid component, where the fatty acid component comprises saturated or unsaturated C4, C5, C6, C7, C8, C9, C10, C11, or C12 fatty acids and/or salts of such fatty acids; and a therapeutic agent. Further, the invention provides a liquid pharmaceutical composition formulated for oral administration by ingestion, comprising: from about 0.1 to about 10% w/v fatty acid component, where the fatty acid component comprises saturated or unsaturated C4, C5, C6, C7, C8, C9, C10, C11, or C12 fatty acids and/or salts of such fatty acids; and a therapeutic agent.
申请公布号 US7605123(B2) 申请公布日期 2009.10.20
申请号 US20050184528 申请日期 2005.07.19
申请人 BIOCON LTD. 发明人 RADHAKRISHNAN BALASINGAM;AGGARWAL DITI;FERRO MICHELLE;JAMES KENNETH D.;MALKAR NAVDEEP B.;MILLER MARK A.;PAVLIV LEO;POLOWY KAREN;PUSKAS MONICA;EKWURIBE NNOCHIRI N.
分类号 A61K38/28 主分类号 A61K38/28
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