N-PHENYLPHOSPHORIC ACID TRIAMIDES, METHOD OF OBTAINMENT AND APPLICATION AS REGULATION AND INHIBITION AGENTS FOR ENZYMIC CARBAMIDE HYDROLYSIS

摘要

FIELD: pharmacology. ^ SUBSTANCE: invention concerns N-phenylphosphoric acid triamides of general formula (I), method of their obtainment and application as inhibition agents in enzymic hydrolysis of carbamide , where X is oxygen or sulphur; R1, R2, R3, R4 are selected out of hydrogen, C1-C8 alkyl, alcoxy, fluorine, chlorine, bromine, iodine, trifluoromethyl. ^ EFFECT: obtaining novel efficient urease inhibitors. ^ 12 cl, 4 ex, 1 tbl