发明名称 |
JAK INHIBITOR |
摘要 |
A JAK inhibitor comprising, as an active ingredient, a nitrogen-containing heterocyclic compound represented by formula (I)
{wherein W represents a nitrogen atom or -CH-;
X represents -C (=O) - or -CHR 4 - (wherein R 4 represents a hydrogen atom, or the like);
R 1 represents the formula described below [wherein Q 1 represents-CR 8 -(wherein R 8 represents a hydrogen atom, substituted or unsubstituted lower alkyl, or the like);
Q 2 represents -NR 15 - (wherein R 15 represents a hydrogen atom, substituted or unsubstituted lower alkyl, or the like); and R 5 and R 6 may be the same or different and each represents a hydrogen atom, halogen, carboxy, substituted or unsubstituted lower alkyl, or the like], or the like; and
R 2 and R 3 may be the same or different and each represents a hydrogen atom, halogen, substituted or unsubstituted lower alkyl, or the like} or a pharmaceutically acceptable salt thereof.
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申请公布号 |
EP2108642(A1) |
申请公布日期 |
2009.10.14 |
申请号 |
EP20070829979 |
申请日期 |
2007.10.17 |
申请人 |
KYOWA HAKKO KIRIN CO., LTD. |
发明人 |
AMISHIRO, NOBUYOSHI;ATSUMI,TOSHIYUKI;NAKAZATO, TOMOYUKI;UMEHARA, HIROSHI;FUJIHARA, HIROAKI;SHINOHARA, FUMIKAZU;FUNAHASHI, JUN;YAMAMOTO, JUNICHIRO;YAGI, KAORI |
分类号 |
C07D209/46;A61K31/404;A61K31/4178;A61K31/4184;A61K31/423;A61K31/4439;A61K31/454;A61K31/4545;A61K31/496;A61K31/506;A61K31/536;A61K31/5377;A61K31/541;A61K31/55;A61P35/00;A61P37/02;A61P43/00;C07D209/48;C07D401/14;C07D403/14;C07D413/04 |
主分类号 |
C07D209/46 |
代理机构 |
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代理人 |
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