| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a stable metastin derivative having excellent bioactivity (cancer metastasis inhibiting activity, cancer growth inhibiting activity, etc.). Ž<P>SOLUTION: This metastin derivative is improved in stability in blood, etc. than natural-type metastin, and shows excellent cancer metastasis inhibiting activity and cancer growth inhibiting activity by modifying the constituting amino acid of metastin with a specific modifying group. This metastin derivative has gonadotropic hormone antisecretory activity, sex-hormone antisecretory activity, etc. which are completely different from the activities known currently. Ž<P>COPYRIGHT: (C)2010,JPO&INPIT Ž
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