发明名称 MANNOSE-6-PHOSPHATE COMPOSITION AND ITS USE IN TREATING FIBROTIC DISORDERS
摘要 PROBLEM TO BE SOLVED: To provide a composition having a wound healing effect at a high concentration to solve the conventional treatment using mannose-6-phosphate which promotes wound healing at high concentration and preventing or mitigating scar formation, but at a high concentration the effects depraves and depraves in comparing with comparison. SOLUTION: Provided is a composition comprising the mannose-6-phosphate formulated by pH adjustment as a suspension or solution at pH 6 to 8, preferably pH 6.5 to 7.5 as a suspension or solution and a suspension or solution of preferably 65 to 300 mM, and a viscous hyaluronic acid gel as a suspending agent, wherein the composition is useful in wound healing, particularly prevention or mitigation of scar formation. COPYRIGHT: (C)2010,JPO&INPIT
申请公布号 JP2009221220(A) 申请公布日期 2009.10.01
申请号 JP20090129987 申请日期 2009.05.29
申请人 BTG INTERNATL LTD 发明人 FERGUSON MARK WILLIAM JAMES
分类号 A61K31/70;A61K31/7024;A61K9/00;A61K9/06;A61K9/08;A61K9/10;A61K47/36;A61L15/44;A61P1/16;A61P17/00;A61P17/02;A61P25/00;A61P27/02;A61P43/00 主分类号 A61K31/70
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