摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide an improved technique for healing or preventing inflammation, damage and other changes that occur prior to, during or immediately after a myocardial failure. <P>SOLUTION: Use of a polypeptide comprising amino acid sequence LKKTET for producing agents for transforming from endothelial cell to mesenchymal cell, or a conservative variant thereof is provided herein. The polypeptide comprises amino acid sequence LKKTET, KLKKTET, LKKTETQ or thymosinβ4(Tβ4), an N-terminal variant of Tβ4, a C-terminal variant of Tβ4, isoform of Tβ4, oxidized Tβ4 or Tβ4 sulfoxide. <P>COPYRIGHT: (C)2010,JPO&INPIT</p> |