发明名称 USE OF THYMOSIN beta4, ANALOGUE, ISOFORM AND OTHER DERIVATIVE
摘要 <p><P>PROBLEM TO BE SOLVED: To provide an improved technique for healing or preventing inflammation, damage and other changes that occur prior to, during or immediately after a myocardial failure. <P>SOLUTION: Use of a polypeptide comprising amino acid sequence LKKTET for producing agents for transforming from endothelial cell to mesenchymal cell, or a conservative variant thereof is provided herein. The polypeptide comprises amino acid sequence LKKTET, KLKKTET, LKKTETQ or thymosinβ4(Tβ4), an N-terminal variant of Tβ4, a C-terminal variant of Tβ4, isoform of Tβ4, oxidized Tβ4 or Tβ4 sulfoxide. <P>COPYRIGHT: (C)2010,JPO&INPIT</p>
申请公布号 JP2009221211(A) 申请公布日期 2009.10.01
申请号 JP20090123032 申请日期 2009.05.21
申请人 REGENERX BIOPHARMACEUTICALS INC 发明人 GOLDSTEIN ALLAN L;FINKELSTEIN JACK JR
分类号 A61K38/00;C12P21/08;A61K38/22;A61K38/27;A61K39/395;A61P9/10;C07K7/06;C07K14/47;C07K16/18;C07K16/26 主分类号 A61K38/00
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