COMPOSITIONS AND METHODS FOR JOINING NON-CONJOINED LUMENS

摘要

Disclosed are compositions, methods, and kits for joining together non-conjoined lumens in a patient's body including vascular lumens, particularly small lumens typically requiring microsurgical technique. Stabilisation of the geomtry of the terminal portions of the tissues having the lumens, faciliutating joining thereof, is achieved by placing a biocompatible composition in a solid state into the terminal portion of at least one lumen. The lumens may then be joined by bonding the tissues with adhesive, for example. The removal of the solid mass can be accomplished using one or more of a number of physical properties of the mass such as melting, phase change where the composition is a phase-reversible sol-gel, change in viscosity, and dissolution in the body fluid.