Simian adenovirus nucleic acid and amino acid sequences, vectors containing same, and methods of use

摘要

Disclosed is a vector having an adenovirus capsid, said capsid comprising a simian adenoviral Pan-5 hexon protein having the amino acid sequence of SEQ ID NO: 3, a sequence having at least 95 to 99% identity with SEQ ID NO: 3, said vector further comprising a heterologous gene operatively linked to sequences which direct expression of said gene in a host cell.