New substituted heterocyclic compounds, compositions containing them, and methods of using them for the inhibition of Raf kinase activity are provided. The new compounds and compositions may be used either alone or in combination with at least one additional agent for the treatment of a Raf kinase mediated disorder, such as cancer.
申请公布号
CA2718936(A1)
申请公布日期
2009.09.24
申请号
CA20092718936
申请日期
2009.03.19
申请人
NOVARTIS AG
发明人
HUANG, ZILIN;JIN, JEFF;MACHAJEWSKI, TIMOTHY D.;ANTONIOS-MCCREA, WILLIAM R.;MCKENNA, MAUREEN;POON, DANIEL;RENHOWE, PAUL A.;SENDZIK, MARTIN;SHAFER, CYNTHIA M.;SMITH, AARON;XU, YONGJIN;ZHANG, QIONG
