发明名称 COMPOUND
摘要 The invention provides a compound (which can act as an adjuvant) of Formula I or Formula (Il), wherein R1 R4 R5 R6 and R7 are each independently selected from hydrogen, acetyl, hydrocarbyl, a lipid moiety and a lipid acyl moiety; R2 is a hydroxyl, a hydrocarbyl, a lipid moiety, a lipid acyl moiety; or an amino hydrocarbyl group optionally substituted with a hydrocarbyl, a lipid moiety or a lipid acyl moiety; R3 and R8 are each independently selected from acetyl, a hydrocarbyl, a lipid moiety and a lipid acyl moiety; X is a peptide chain; The above normuramylglycopeptide compounds can be located in liposomes and micelles and can function as immunomodulators, along with a desired antigen (or DNA encloding the antigen), in (e.g. DNA) vaccines.
申请公布号 WO2009115782(A2) 申请公布日期 2009.09.24
申请号 WO2009GB00703 申请日期 2009.03.17
申请人 IMUTHES LIMITED;INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY AV CR, V.V.I.;VYZKUMNY USTAV VETERINARNIHO;HIPLER, KARSTEN;MILLER, ANDREW;TURANEK, JAROSLAV;LEDVINA, MIROSLAV 发明人 HIPLER, KARSTEN;MILLER, ANDREW;TURANEK, JAROSLAV;LEDVINA, MIROSLAV
分类号 C07K9/00;A61K38/04 主分类号 C07K9/00
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