| 发明名称 |
COMPOSITIONS AND METHODS TO TREAT MUSCULAR AND CARDIOVASCULAR DISORDERS |
| 摘要 |
The present invention relates to a novel microRNA, mir-208-2, implicated in muscular and cardiovascular disorders. The present invention also relates to oligonucleotide therapeutic agents (antisense oligonucleotides and/or double stranded oligonucleotides such as dsRNA) and their use in the treatment of muscular and cardiovascular disorders resulting from dysregulation of mir-208-2.
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| 申请公布号 |
KR20090098818(A) |
申请公布日期 |
2009.09.17 |
| 申请号 |
KR20097012148 |
申请日期 |
2007.12.13 |
| 申请人 |
NOVARTIS AG |
发明人 |
BEUVINK IWAN;HALL JONATHAN;WEILER JAN;SCHNELL CHRISTIAN;MUELLER MATTHIAS;SCHINKE BRAUN MARTINA;SERLUCA FABRIZIO |
| 分类号 |
A61K48/00;A61P9/00;A61P21/00;C12N15/113 |
主分类号 |
A61K48/00 |
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