The present invention provides an orally-disintegrating solid preparation such as a tablet produced by tabletting fine granules showing controlled release of a pharmaceutically active ingredient and an additive, and the like, and the orally-disintegrating solid preparation containing fine granules coated with a coating layer containing a polymer affording a casting film having an elongation at break of about 100 - about 700%. With the preparation, breakage of fine granules during tabletting can be suppressed in the production of an orally-disintegrating solid preparation containing fine granules showing controlled release of a pharmaceutically active ingredient.
申请公布号
WO2009113703(A2)
申请公布日期
2009.09.17
申请号
WO2009JP54983
申请日期
2009.03.10
申请人
TAKEDA PHARMACEUTICAL COMPANY LIMITED;KURASAWA, TAKASHI;WATANABE, YASUKO;OMACHI, YOSHIHIRO