发明名称 |
Bis(thio-hydrazide amide) compounds in combination with taxol for treating cancer |
摘要 |
<p>There is provided a compound of formula (I):
or a pharmaceutically acceptable salt thereof, wherein Y, Z and R 1 to R 6 have meanings given in the description, for use in the treatment of melanoma or renal cancer by administration of said compound, in the same or separate pharmaceutical composition, with paclitaxel or a paclitaxel analog. There is also provided the use of a compound of formula (I) for the production of a medicament for administration, in the same or separate pharmaceutical composition, with paclitaxel or a paclitaxel analog, for treating melanoma or renal cancer.</p> |
申请公布号 |
EP2100605(A1) |
申请公布日期 |
2009.09.16 |
申请号 |
EP20090004577 |
申请日期 |
2002.07.10 |
申请人 |
SYNTA PHARMACEUTICALS CORPORATION |
发明人 |
KOYA, KEIZO;SUN, LIJUN;CHEN, SHOUJUN;TATSUTA, NORIAKI;WU, YAMING;ONO, MITSUNORI;XIA, ZHI-QIANG |
分类号 |
A61K31/337;C07D213/77;A45D8/00;A45D8/12;A45D8/20;A45D8/36;A61K;A61K31/16;A61K31/165;A61K31/197;A61K31/34;A61K31/4035;A61K31/444;A61K31/5355;A61P;A61P35/00;C07C;C07C327/00;C07C327/56;C07D209/42;C07D209/44;C07D213/83;C07D261/18;C07D307/68;C07D333/38;C07D333/68 |
主分类号 |
A61K31/337 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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