KETOCONAZOLE-DERIVATIVE ANTAGONISTS OF HUMAN PREGNANE X RECEPTOR AND USES THEREOF
摘要
<p>The application discloses ketoconazole derivatives that are antagonists of the human pregnane X receptor (PXR), methods of preparing the derivatives, uses of the derivatives with drug therapy, and methods of inhibiting tumor cell proliferation and multidrug resistance using inhibitors of PXR.</p>
申请公布号
WO2009110955(A2)
申请公布日期
2009.09.11
申请号
WO2009US00524
申请日期
2009.01.27
申请人
ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY;MANI, SRIDHAR;DAS, BHASAR, C.
