| 发明名称 |
COVALENTLY BINDING IMAGING PROBES |
| 摘要 |
The present invention relates to molecular probes of the formula (I) L1-R1-L-A-X as defined herein that allow for the observation of the catalytic activity of a selected capase, cathepsin, MMP and carboxypeptidase in in vitro assays, in cells or in multicellular organisms, a method for their preparation and the use thereof. |
| 申请公布号 |
WO2009103432(A2) |
申请公布日期 |
2009.08.27 |
| 申请号 |
WO2009EP00815 |
申请日期 |
2009.02.06 |
| 申请人 |
SANOFI-AVENTIS;WENDT, KARL-ULRICH;KINDERMANN, MAIK;MINIEJEW, CATHERINE;GLOBISCH, ANJA |
发明人 |
WENDT, KARL-ULRICH;KINDERMANN, MAIK;MINIEJEW, CATHERINE;GLOBISCH, ANJA |
| 分类号 |
C07D277/42;A61K31/495;C07D403/12;C07D413/12 |
主分类号 |
C07D277/42 |
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