摘要 |
FIELD: chemistry, biochemistry. ^ SUBSTANCE: invention relates to biotechnology and represents method of obtaining purine nucleosides, such as inosine and guanosine, as well as method of obtaining 5'-inosinic acid or 5'-guanylic acid, using bacteria belonging both to genus Escherichia, and to genus Bacillus, in which production of said nucleosides by said bacteria is enhanced due to increase of activity of protein, coded by gene yeaS (leuE). ^ EFFECT: obtaining purine nucleosides and nucleotides with high degree of efficiency. ^ 7 cl, 2 dwg, 3 tbl, 5 ex |