发明名称 |
Alpha 7 Nicotinic Receptor Selective Ligands |
摘要 |
The invention relates to the design and synthesis of 3-arylidene-anabaseine compounds that exhibit enhanced selectivity toward alpha7 nicotinic receptors. The compounds are expected to be useful in treating a wide variety of conditions, including neurodegenerative conditions such as Alzheimer's Disease, neurodevelopmental diseases such as schizophrenia, and certain peripherally located inflammations mediated by macrophage infiltration.
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申请公布号 |
US2009215705(A1) |
申请公布日期 |
2009.08.27 |
申请号 |
US20060921832 |
申请日期 |
2006.06.07 |
申请人 |
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. |
发明人 |
KEM WILLIAM R.;SOTI FERENC |
分类号 |
A61K31/7028;A61K31/444;A61P25/00;C07D213/22;C07D401/14;C07D405/14;C07H15/00 |
主分类号 |
A61K31/7028 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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